Inflammation is the body’s defense mechanism against any foreign invasion for example, a virus, bacteria or fungal infection. This response is also illicit upon injury or trauma causing a break in the skin and entrance of a foreign body or dust.
An injury or illness can involve acute, or short-term, inflammation.
There are five key signs of acute inflammation:
- Pain: This may occur continuously or only when a person touches the affected area.
- Redness: This happens because of an increase in the blood supply to the capillaries in the area.
- Loss of function: There may be difficulty moving a joint, breathing, sensing smell, and so on.
- Swelling: A condition call edema can develop if fluid builds up.
- Heat: Increased blood flow may leave the affected area warm to the touch.
Inflammation in the mouth can be in the gingiva, inside of the cheek and under the tongue and tonsillar areas of the mouth
There can be many causes for inflammation, the most common being due to gingivitis or periodontitis. This appears as swollen red and painful gums which bleed on probing and brushing. The most common cause of gingivitis is accumulation of plaque over long periods of time and food impaction. This causes hardening of plaque in to tartar which is no longer removed by simple tooth brushing. The bacteria present in the plaque starts acting on the food debris and sugar present in the mouth and breaks it down to release acid and toxins. The acid is disastrous for teeth as it starts to erode the enamel of the teeth resulting in cavity formation encouraging more food to get lodged in the teeth. The host tissues present in the gingiva respond to the accumulation of tartar by the process of inflammation. This is a process in which the innate immune system get activated, in response to exogenous and endogenous factors, such as infection by microorganisms, tissue stress, and injuries. Inflammation is a protective response, characterized by its cardinal signs, such as redness, swelling, heat, pain, and disrupted function innate, inflammatory, and adaptive reactions are triggered. If left untreated, as in the case of chronic infections repeated processes result in the destruction of the tissues that surround and support the teeth, and eventually in the loss of tissues, bones and finally, of the teeth.
Other causes of inflammation in the mouth are mouth sores and ulcers in the form or cold sores or canker sores. These oral ulcerations are common painful lesions that are related to various conditions ranging from minor local trauma to significant systemic conditions, such as hematological, gastroenterological, dermatological, and immunological diseases and malignancies Oral mucositis due to chemotherapy and radiotherapy represents a problematic side effect in cancer treatment.
Anti Inflammatory Effects of Thymoquinine in Black Seed Oil
Many experimental studies have been conducted to test the effects of black seed oil in medicine. It has been used for over centuries in medicine to cure many diseases including asthma, gastro intestinal and infertility problems as well as in wound healing. Here black seed oil and its active ingredient thymoquinone is being tested for anti-inflammatory effects.
Topical black seed oil was found to have a good therapeutic effect on the healing of chemically induced oral ulcers, according to an experiment carried out on 12 rabbits by Al Douri and Al Kazaz. The authors created the ulcers with 0.3 ml of 1% formalin injections in the cheek mucosa of the rabbits followed by topical application of black seed oil twice a day for 3 days. The animals were sacrificed on the fifth day, and their cheek mucosae were histologically examined. The results showed a significant healing process enhancement with black seed oil treatment and there was a marked difference between them and the control groups. The authors of the study justified the results by asserting that the black seed oil accelerated the healing of ulcers, because it inhibited the growth of pathogenic organisms at the site of the ulcers. Healing process. Moreover, the TQ flavonoids and the other components in the black seed oil (vitamins and minerals) make it an excellent promoter of ulcer healing.
A study in a rat model evaluated the capacity of black seed oil to decrease the severity of chemotherapy-induced mucositis. In that study, male albino rats were divided randomly into 3 groups: control, untreated, and treated. The results showed that in comparison with controls and untreated rats, black seed oil decreased the histologically observed damage of the cheek mucosa in the mucositis model. The results suggested black seed oil as a promising preventive adjunct to conventional chemotherapy for reducing the severity of oral mucositis.
Bone healing/socket and implants
Recently, it has been reported that black seed induced bone healing in extracted teeth sockets and manifested faster bone trabeculae formation.this was an animal study, in which the therapeutic effect of both powder and oil forms of black seed on socket healing were investigated. The results showed an early detection of osteoid formation at the first week and bone trabeculae formation at the 6th week in sockets treated with black seed (powder and oil). However, in the histological study, it was found that at the extraction sites, black seed powder was more effective than the black seed oil in terms of bone formation.
SprinJene Natural Toothpaste
Keeping in mind its immense health benefits and positive effects in the oral mucosa, black seed oil has proven to be an excellent ingredient for dental products without any reported side effects.
SprinJene Natural Toothpaste range has a patented black seed oil formula and along with that incorporates the following natural ingredients which are known to combine together to make an excellent tooth paste:
Black seed oil - Known to have excellent antimicrobial and anti-inflammatory properties
Zinc- Helps control the growth of bacteria, plaque and tartar thereby promoting healthy gums. ADA Approved
Acacia gum - A natural organic binder
Xylitol and Stevia- non cariogenic natural sweeteners. Xylitol helps promote saliva production and prevents tooth decay. It is also ADA approved.
Coconut oil - Helps lubricate oral surfaces to bring comfort to dry mouth sufferers and may help to prevent tooth decay after some enzyme digestion.
Green apple and Mint extracts - Taste modifiers with cooling sensation.
Aqua - Solvent to solubilize salts. Formulation aid.
Silica- Natural abrasives to assist stain removal.
Glycerin - Glycerin is a non-carcinogenic and a Non-GMO humectant that helps protect our formulas against bacteria growth and keep the product moist.
In addition to these properties SprinJene is a certified Gluten free toothpaste making it 100% safe for people suffering from Celiac disease and gluten allergies.